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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1
All Species:
48.18
Human Site:
Y274
Identified Species:
75.71
UniProt:
P48729
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48729
NP_001020276.1
337
38915
Y274
R
F
E
E
A
P
D
Y
M
Y
L
R
Q
L
F
Chimpanzee
Pan troglodytes
XP_001163892
341
39357
Y278
R
F
E
E
A
P
D
Y
M
Y
L
R
Q
L
F
Rhesus Macaque
Macaca mulatta
XP_001106705
339
39093
Y276
R
F
E
E
A
P
D
Y
M
Y
L
R
Q
L
F
Dog
Lupus familis
XP_867638
336
38749
Y274
R
F
E
E
A
P
D
Y
M
Y
L
R
Q
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
Y266
R
F
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
Rat
Rattus norvegicus
P97633
325
37477
Y262
E
F
A
M
Y
L
N
Y
C
R
G
L
R
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
Y274
R
F
E
E
A
P
D
Y
M
Y
L
R
Q
L
F
Frog
Xenopus laevis
Q5BP74
415
47421
Y266
R
F
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
Y266
R
F
D
D
K
P
D
Y
S
Y
L
R
Q
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
E273
C
R
S
L
R
F
E
E
Q
P
D
Y
M
Y
L
Honey Bee
Apis mellifera
XP_393612
350
40282
Y278
R
F
E
E
S
P
D
Y
M
Y
L
R
Q
L
F
Nematode Worm
Caenorhab. elegans
P42168
341
39018
Y273
R
F
D
E
S
P
D
Y
M
Y
L
R
Q
L
F
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
E284
A
R
G
L
R
F
D
E
N
P
D
Y
V
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
Y266
R
F
D
D
K
P
D
Y
A
Y
L
K
R
I
F
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
Y266
K
F
D
E
K
P
D
Y
L
F
L
A
R
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.6
99.6
N.A.
57.2
96.1
N.A.
N.A.
99.6
57.5
59.5
N.A.
74.1
80.8
81.2
78.7
Protein Similarity:
100
98.8
98.2
99.6
N.A.
67.7
96.1
N.A.
N.A.
100
67.9
70.2
N.A.
82.7
86.8
86.8
87.3
P-Site Identity:
100
100
100
100
N.A.
73.3
13.3
N.A.
N.A.
100
73.3
73.3
N.A.
0
93.3
86.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
N.A.
100
86.6
86.6
N.A.
6.6
100
100
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.2
41.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.1
54.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
34
0
0
0
7
0
0
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
40
27
0
0
87
0
0
0
14
0
0
0
0
% D
% Glu:
7
0
40
54
0
0
7
14
0
0
0
0
0
0
7
% E
% Phe:
0
87
0
0
0
14
0
0
0
7
0
0
0
7
80
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
7
0
0
0
34
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
14
0
7
0
0
7
0
80
7
0
74
14
% L
% Met:
0
0
0
7
0
0
0
0
47
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
80
0
0
0
14
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
67
0
0
% Q
% Arg:
74
14
0
0
14
0
0
0
0
7
0
67
20
0
0
% R
% Ser:
0
0
7
0
14
0
0
0
20
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
87
0
74
0
14
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _